Thermo Fisher Applied Biosystems Genetic Analyzers

August 4, 2026·Source: CISA

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TL;DR

View CSAF Summary Successful exploitation of this vulnerability could allow an attacker to modify .fsa/.hid output files, tampering with DNA data and resulting in inaccurate test results. The following versions of Thermo Fisher Applied Biosystems Genetic Analyzers are affected: Applied Biosystems 3500/3500xL Series Data Collection Software <=4.0.2 Applied Biosystems 3730/3730xL Series Data Collection Software <=5.0.2 Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software <=1.2.5 Applied Biosystems SeqStudio Flex Series Instrument Software <=1.2.0 Applied Biosystems GeneMapper ID-X Software <=v1.7.3 Applied Biosystems 3130 Series Data Collection Software <=4.1 ABI PRISM 3100/3100-Avant Data Collection Software <=2.0 ABI PRISM 310 Data Collection Software <=3.1 CVSS Vendor Equipment Vulnerabilities

v3 8.4 Thermo Fisher Thermo Fisher Applied Biosystems Genetic Analyzers Missing Support for Integrity Check

Background Critical Infrastructure Sectors: Healthcare and Public Health Countries/Areas Deployed: Worldwide Company Headquarters Location: United States Vulnerabilities Expand All + CVE-2026-17583 The affected product is vulnerable because its .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes. View CVE Details Affected Products Thermo Fisher Applied Biosystems Genetic Analyzers Vendor: Thermo Fisher Product Version: Thermo Fisher Applied Biosystems 3500/3500xL Series Data Collection Software: <=4.0.2, Thermo Fisher Applied Biosystems 3730/3730xL Series Data Collection Software: <=5.0.2, Thermo Fisher Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software: <=1.2.5, Thermo Fisher Applied Biosystems SeqStudio Flex Series Instrument Software: <=1.2.0, Thermo Fisher Applied Biosystems GeneMapper ID-X Software: <=v1.7.3, Thermo Fisher Applied Biosystems 3130 Series Data Collection Software: <=4.1, Thermo Fisher ABI PRISM 3100/3100-A

What Happened

Thermo Fisher Applied Biosystems Genetic Analyzers, reported by CISA.

v3 8.4 Thermo Fisher Thermo Fisher Applied Biosystems Genetic Analyzers Missing Support for Integrity Check

For the full technical details, see the original report.

Why It Matters for Businesses

This development could affect organizations that rely on the impacted technologies or services. Unpatched systems, misconfigured infrastructure, or lack of monitoring can leave businesses exposed to exploitation, data breaches, and regulatory penalties.

How to Check Your Exposure

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Mitigation Steps

Patch immediately, Apply vendor patches or updates as soon as they are available.
Review configurations, Check firewall rules, access controls, and security headers.
Monitor logs, Watch for indicators of compromise (IOCs) related to this threat.
Update security policies, Ensure incident response plans cover this type of threat.
Run a security scan, Use automated tools to verify your exposure.

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